Could mRNA vaccines alter DNA? Harvard scientist says it’s possible

Research on SARS-CoV-2 RNA by scientists at Harvard and MIT has implications for how mRNA vaccines could permanently alter genomic DNA, according to Doug Corrigan, Ph.D., a biochemist-molecular biologist who says more research is needed.

…The preliminary evidence cited by the Harvard-MIT researchers indicates that endogenous reverse transcriptase enzymes may facilitate reverse transcription of coronavirus RNAs and trigger their integration into the human genome.

The authors suggest that while the clinical consequences require further study, detrimental effects are a distinct possibility and — depending on the integrated viral fragments’ “insertion sites in the human genome” and an individual’s underlying health status — could include “a more severe immune response … such as a ‘cytokine storm’ or auto-immune reactions.”

In 2012, a study suggested that viral genome integration could “lead to drastic consequences for the host cell, including gene disruption, insertional mutagenesis and cell death.”

Could mRNA Vaccines Permanently Alter DNA? Recent Science Suggests They Might.

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