Study Finds ‘Cannabinoids Hold Significant Potential for Preventing and Treating Brain Diseases’

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Conducted by researchers from Qingdao University, the study highlights the impact of cannabinoids on neuroinflammation, oxidative stress, apoptosis, autophagy, and neurogenesis.

According to the study, cannabinoid receptors (CBRs) mediate these functions through several inflammatory pathways, including nuclear factor-κB (NF-κB), NOD-like receptor protein 3 (NLRP3) inflammasome, mitogen-activated protein kinase (MAPK), protein kinase B (Akt), and cAMP-dependent protein kinase (PKA). A key focus of the research is microglia, the primary immune cells in the CNS responsible for mediating neuroinflammation. By influencing these pathways, cannabinoids may help regulate immune responses and cellular health in the brain.

The study also presents a table summarizing the role of cannabinoids in various brain diseases, emphasizing their protective effects in neurological conditions. The authors propose that cannabinoids could be useful in preventing and treating disorders related to ferroptosis, lactate metabolism, and mitophagy—three biological processes associated with neurodegeneration.

The study concludes:

Medical use of cannabinoids has protective effects in preventing and treating brain diseases; however, excessive and repeated use can be detrimental to the CNS. We propose that cannabinoids hold significant potential for preventing and treating brain diseases, including ferroptosis, lactate metabolism, and mitophagy, providing new insights for further research on cannabinoids.

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From what I have been reading over the years, these findings are corroborated by many other researchers. The main takeaway I see is very low dose usage of cannabinoids is beneficial but high doses are not. If cannabis is keeping you away from alcohol or other worse drugs, it would be a good thing. Cannabis does seem to help prevent alcoholism, which is one of the worst addictions. The Buddha strongly advised against the ‘irresponsible use of alcohol’ by laypeople. It’s the fifth precept of the Five Precepts of Buddhism. It is telling that the Buddha did not mention other intoxicants, only alcohol. I say this because too many today interpret the fifth precept as being against all kinds of intoxicants when only alcohol is denoted. Obviously, many other intoxicants are not good either, but I do see plenty of room for judicious use of some psychedelics and/or cannabis for some people sometimes. Both of these drugs were well-known in the Buddha’s day and he would have mentioned them if he had wanted to. ABN

Netflix star Kim Sae-ron dies aged 24: Actress who starred in hit K-drama Bloodhounds found dead in her home as fans pay tribute

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South Korean Netflix star Kim Sae-ron has died at the age of 24, according to police. 

Tributes have poured in for the actress who found fame on the streaming service’s hit show Bloodhounds. 

Kim was found dead at her home by a friend who alerted police on Sunday. It is not believed there are any suspicious circumstances, police have said. 

She was one of the most promising actresses in South Korea, but her career took hit after a drink driving incident in 2022.

Kim first appeared on screen at just nine years old and gained roles in a number of films and TV shows. 

She rose in popularity as a child star in the 2009 film A Brand New Life and 2010’s The Man From Nowhere.

Kim later got her debut adult role in the 2016 TV drama Secret Healer and also appeared in the 2018 thriller The Villagers.

Her last performance was in the Korean drama series Bloodhounds which was released on Netflix in 2023.

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Beta-testing full surveillance state coming soon

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I definitely see the bad but some good may come of this. NSA has the data on the parasite which has infested our country. Used properly, they can target all of it simultaneously and remove it. This could happen with a big splash or be done quietly with almost no one noticing. Either way, the result would be a much cleaner and more efficient nation with much less violence. Time will tell. ABN

Allowing Ivermectin to be Available Over the Counter in Pennsylvania — Senator Doug Mastriano

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I am pleased to announce that I will be introducing legislation to allow ivermectin, a proven antiparasitic medication, to be sold over the counter (OTC) in Pennsylvania. This important proposal aims to enhance access to this safe and effective treatment for various parasitic conditions, empowering residents to manage their health more efficiently.

Ivermectin is an FDA-approved medication primarily used for treating infections such as river blindness, strongyloidiasis, scabies, and lice. With a long history of safe use, this legislation is designed to have a positive impact on public health, especially in underserved and rural communities.

Key benefits of this proposal include:

Increasing Access to Critical Medication: Residents will have faster access to ivermectin, reducing wait times and lessening dependency on healthcare providers for conditions that do not require extensive consultation. This is particularly beneficial for those in rural areas facing healthcare barriers.

Proven Safety and Effectiveness: Ivermectin has been extensively studied and shown to have minimal side effects when used as directed, making its topical formulations safe and easy to apply.

Supporting Public Health: Allowing OTC access could help control the spread of parasitic diseases like scabies, while also reducing the burden on healthcare systems by decreasing unnecessary emergency visits for manageable conditions.

Encouraging Health Autonomy: By removing the prescription requirement, individuals can take charge of their health regarding preventative care for minor conditions. Pennsylvania joins a growing movement, with states like Tennessee already passing similar legislation and others considering it. Countries including South Africa, Australia, and Mexico have successfully implemented OTC access to ivermectin as well.

It is time for Pennsylvania to make this necessary change. With proven efficacy and a strong safety record, enabling over-the-counter access to ivermectin will significantly benefit our communities.

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Note: Ivermectin used to be OTC in France, but was made prescription-only in early January 2020, before covid was widely known about. This is one of many suspicious details surrounding and presaging the plandemic. Removing an easy cure just before the plandemic was declared, looks very much like a setup for the vax as bioweapon. Some months after that, ivermectin was resolutely banned in the West, excoriated and mocked, y’all. Looking back on those days and those deadly, absurd policies, it is hard to believe covid itself plus the vaxxes, plus the forced hospitalizations and lethal treatments were not sinister acts of war against the people of the West (in particular). Others also suffered but the main target was clearly the West. ABN

DOGE zeroes out the National Endowment for Democracy

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The DOGE team has now taken the step, reported earlier this week, of freezing government payments to the National Endowment for Democracy, a private organization that in 2023 received a $315 million appropriation from Congress, paid via the State Department. That is big news in Washington because the NED, a nongovernmental organization that depends on federal funds, has survived numerous attempts over the years to close it down and up to now has maintained a bipartisan consensus to keep it in business. The move to cut off the organization’s funding suggests that its bipartisan support has at last broken down.

The order from DOGE to freeze further disbursements to the NED has paralyzed the organization, according to news reports. “It’s been a bloodbath,” one NED staffer said. “We have not been able to meet payroll and pay basic overhead expenses.” It sounds as if what happened to USAID last week has now happened to the NED.

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‘I don’t know why she said nothing as DOJ did Russiagate, false FISA warrants, cartoonish overprosecution of J6ers, Mar-a-Lago raid, refusing to enforce border laws’ — Mollie Hemmingway

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NeverTrumpers are praising Danielle Sassoon for resigning from the DOJ’s Southern District New York rather than comply with the new DOJ policy against weaponized investigations and prosecutions. Usually they emphasize her affiliations … a few quick thoughts… 

1) if you do not want to comply with a policy, the right thing to do is resign. I don’t know why she said nothing as DOJ did Russiagate, false FISA warrants, cartoonish overprosecution of J6ers, Mar-a-Lago raid, refusing to enforce border laws, etc. but nevertheless, if she wanted to continue what had been deemed a political prosecution, she can resign. 

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Louisiana Dept Of Health ‘Will No Longer Promote Mass Vaccination’

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Following Robert F. Kennedy Jr.’s confirmation as the secretary of Health and Human Services (HHS), the Louisiana Department of Health (LDH) confirmed that it “will no longer promote mass vaccination.”

The announcement by the LDH was sent out as an internal memo — ordering staff to end all media campaigns and promotions to encourage vaccinations.

“The State of Louisiana and LDH have historically promoted vaccines for vaccine preventable illnesses through our parish health units, community health fairs, partnerships and media campaigns,” wrote Louisiana’s Surgeon General Ralph Abraham.

“While we encourage each patient to discuss the risks and benefits of vaccination with their provider, LDH will no longer promote mass vaccination,” the memo continued.

The LDH also released a public statement, vowing to restore the public’s trust in the healthcare system following the previous COVID-19 mandates and lockdowns.

“For much of the last century, public health has taken it upon itself to fill the gaps in our broken healthcare system – providing guidance, information, and health recommendations. But when we get it wrong and overreach, the harm is often irreparable. Trust is built over years and lost in seconds, and we’re still rebuilding from the COVID missteps,” the announcement read.

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Very good news. Covid proved we the people are smarter than government bureaucrats and that free speech is better than government restricted speech. I hope everyone who lived through that era will always remember how much free speech and free choice in medicine matters. ABN

Silk Road merchants may have introduced cats to China 1400 years ago

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…an analysis of the largest ever collection of ancient cat bones in China—reported this month on the preprint server bioRxiv—suggests housecats may have arrived in the country around 600 C.E., hundreds of years after they set paw in Europe. They appear to have been brought by merchants from the West, traveling along the famed Silk Road.

“It’s a knockout study,” says Melinda Zeder, an archaeozoologist at the Smithsonian Institution’s National Museum of Natural History who was not involved with the work. Cats recently became the most popular pet in urban China, and the new research helps clarify how they first got there, she says. “Tying them to the Silk Road is really boffo.”

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Rate of marriages in China lowest since record keeping began in 1986, with cost of living and pushback against traditional gender roles contributing factors

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Marriages in China plunged 20% to a record low in 2024 as young people resisted government efforts to convince them to settle down and have more babies.

Marriages in China dropped from 7.7m in 2023 to 6.1m last year, data from China’s civil affairs ministry showed. The figure was less than half the number registered in 2013, and the lowest since record keeping began in 1986.

The data also showed that 2.6 million couples filed for divorce in 2024, up 1.1% from the previous year.

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Contagion teams spread poisons and also kill

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Not just for vaxxes but also for anything and everything that undermines USA. Poison, murder, sensory damage done in secret, psychosurgery. Different people see what is happening from different angles. Vaxxes are but one vector. This country has not been lost through ideas alone, as too many intellectuals believe. There has been and is massive real violence at many societal levels. The NSA should have the information that connects the perps. It is my hope that DOGE is ‘merely’ a foot in the door that will lead to full eradication of the parasite that has infested USA. ABN