In conclusion, in a set of patients who underwent PET/CT for indications other than myocardial inflammation, those who had received a SARS-CoV-2 vaccination showed increased myocardial FDG uptake on images up to 180 days after their 2nd vaccination compared to patients imaged before SARS-CoV-2 vaccination was available. Vaccinated patients showed higher myocardial FDG uptake on PET/CT compared to nonvaccinated patients regardless of sex, age, or type of mRNA vaccine received. A prospective study would be needed to validate the findings of this study including comparisons with cardiac enzyme, cardiac functions and non-mRNA vaccination.
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