New cultivation methods are making psychedelic mushrooms stronger, and fiendishly potent varieties are kicking in faster and lasting longer—even if you eat only a fraction of what you would with another variety. Subsequent testing showed that one batch of Mattucci’s mushrooms contained almost 5 percent psychedelic alkaloids, which was once unheard of within the Psilocybe genus. Typically, mushrooms contain 1 percent of these psychoactive compounds, although species like Psilocybe azurescens are generally stronger, and some varieties within the Panaeolus genus are even more potent.