COVID-19 mRNA Shots Destroy Over 60% of Women’s Non-Renewable Egg Supply

New study finds rats injected intramuscularly with human-equivalent mRNA doses suffered irreversible loss of primordial follicles — the foundation of fertility.

…Here’s what the study found in simple terms:

Severe Destruction of Ovarian Reserve

• Rats injected intramuscularly with a Pfizer-BioNTech COVID-19 mRNA vaccine — at a human-equivalent dose — experienced a >60% reduction in primordial follicles, the foundational egg supply for future fertility (p < 0.001).
• The inactivated vaccine (CoronaVac) also caused loss, but to a lesser extent.

Damage Targets Non-Renewable Egg Supply

• The primordial follicle pool is finite and non-regenerating — females are born with all the eggs they will ever have.
• Destruction of this pool is irreversible, leading to permanent fertility loss if translated to humans.

Anti-Müllerian Hormone (AMH) Levels Crashed

• AMH, a hormone reflecting ovarian reserve, dropped significantly in the mRNA group — both in serum and in ovarian tissue (p < 0.001).
• Lower AMH is associated with poor fertility outcomes and earlier menopause.

Elevated Cell Death and Inflammatory Signals

• Increased expression of caspase-3 (a cell-death enzyme) and inflammatory markers like TGF-β1 and VEGF were found in vaccinated rats.
• These biomarkers are linked to ovarian atresia, fibrosis, and long-term tissue damage.

More Severe Effects with mRNA Vaccines

• Compared to the inactivated vaccine, the mRNA group had:
  • Fewer growing follicles (primary, secondary, antral, preovulatory)
  • More dying follicles (atretic)
  • Greater reductions in hormone markers of fertility

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If these findings indeed apply to humans, the implications for global fertility rates are profound. This kind of damage — to a woman’s lifelong egg supply — is biologically irreversible.

Unfortunately, a recent study by Manniche et al indicates that these ovarian reserve destruction findings likely DO translate to humans. Among ~1.3 million Czech women aged 18–39, those vaccinated against COVID-19 had ~33% fewer successful pregnancies compared to unvaccinated women:

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