First-ever gene therapy trial to cure form of deafness begins
Professor Manohar Bance, an ear surgeon at Cambridge University Hospitals NHS Foundation Trust who is leading the trial in the UK, said a decision by the NHS last year to start funding genetic testing for hearing loss had been crucial in “changing the whole landscape” for the development of gene therapies.
Gene therapies now held remarkable promise to restore hearing, he suggested. “It’s the dawn of a new era,” he added.
Auditory neuropathy can be due to a variation in a single gene—known as the OTOF gene—which produces a protein called otoferlin. This protein typically allows the inner hair cells in the ear to communicate with the hearing nerve.
Mutations in the OTOF gene can be identified by genetic testing. However, Bance said it was a condition often missed when newborn babies were screened for potential hearing problems. “This is one of the few conditions where everything works except the transmission between the hair cells and the nerve. So everything else looks fine when you test it, but they can’t hear anything. So these poor kids’ [difficulties] end up being missed,” Bance added.
The new gene therapy aims to deliver a working copy of the faulty OTOF gene using a modified, non-pathogenic virus. It will be delivered via an injection into the cochlea under general anesthetic.
Email exchange on war & power in today’s world
It is a strange time. Because there was some kind of takeover full domination and depopulation plan, yet it was based on also having hegemony. Hegemony is breaking down, but the domination and depopulation plan is still in motion. Maybe this is how it should go, but it doesn’t seem that way. Maybe there is a notion they can do both at once—however this seems epically stupid. Also it seems this whole plan was put into motion by people who are now geriatric hard to know because it is all secret.
I do suspect British Royal Family and other euro royals are big players. Then organizations set up by the American robber barons in the Early 1900s. That used to all be quite naked to the public but the advent of PR put it in the shadows. The UK royals are all in on the money and put their faces everywhere in Canada and Australia. Much like you see the UAE royals have shops and hotel all put up portraits of them. That is Raw power. Much like Xi making everyone study Xi thought.
The one thing that got me thinking lately is the economic cost of a wrong view. I mean each wrong view likely costs us some amount as we make poorer decisions about everything else. Think of the economic cost of someone vaccine injured. But then all the other bits of lack of information. How much time we spend on such things. And then the cost to society when people are massively misinformed.
J
I agree with what you say and also I think the possibility must be considered that the cabal in the West has a super weapon which nobody knows about but them. This weapon would be powerful enough to ensure victory against any and all opponents on Earth. I do believe this is a real possibility and cannot be dismissed.
Continue reading “Email exchange on war & power in today’s world”Former Hamas leader Khaled Meshaal calls for day of jihad on Friday the 13th, and tells Muslims to ‘take to the streets’ in protest against Israel
A former Hamas chief has called for protests to take place across the Muslim world on Friday in support of the Palestinians, and for the peoples of neighboring countries to join the fight against Israel.
‘[We must] head to the squares and streets of the Arab and Islamic world on Friday,’ said Khaled Meshaal, who currently heads Hamas’s diaspora office.
Meshaal, who is based in Qatar, said the governments and peoples of Jordan, Syria, Lebanon and Egypt have a bigger duty to support the Palestinians.
‘Tribes of Jordan, sons of Jordan, brothers and sisters of Jordan… This is a moment of truth and the borders are close to you, you all know your responsibility,’ Meshaal said in a recorded statement. ‘To all scholars who teach jihad… to all who teach and learn, this is a moment for the application (of theories).’
Jordan and Lebanon are home to the largest number of Palestinian refugees.
Steve Bannon — What happened in Israel ‘is coming to USA as sure as the turning of the earth’
There is a strong possibility that tomorrow, Friday 13th, there will be Hamas attacks in USA. The MIHOP attacks in Israel may lead to what are fundamentally MIHOP attacks in USA; MIHOP since the Biden admin allowed untold numbers of bad actors to pour across the border. A consequence of attacks in USA will be an enraged American population dying to be sucked into another world war. Just a few savage attacks will change the mood of this country overnight, especially since we have all been primed by the violent raid in Israel. Ukraine primed us as well. I am not saying it will definitely happen but the conditions to go to war with Iran and more are all in place. I see two other factors: 1) the cabal that controls the West, including Israel, is incompetent and has lost touch with reality and may bring debacle; or 2) they have a super weapon that ensures a decisive and violent win. If point two is correct, their incompetence has been a ruse to fool their enemies. ABN
White House signals end of funding for Ukraine War: Kirby — funding ‘near to the end of the rope… not going to be indefinite’
The attack in Israel has provided the offramp for US neocon/ NATO hot action in Ukraine, for now anyway. This pot will still be on the stove simmering. If you are going for global domination, you have to have a big stove. Today’s geopolitical conditions can best be understood in light of some assumptions about how top cabal actors understand the world and what they want. What they want is unequivocal global domination and this means all parts of the world are in play and no populations are especially respected. Witness the MIHOP attacks in Israel. An attack on Iran will constitute an attack on BRICS, as will messing with China and Russia. Central Asia was the center of Zbigniew Brzezinski’s Grand Chessboard and appears to be so today as well. ABN
SHOCK MOMENT: Trump Says ‘Bibi Netanyahu Let Us Down’ In Soleimani Strike But ‘Tried To Take Credit’
How Hamas Turned an Israeli Music Festival Into a Massacre | WSJ
‘If you want a picture of the future, imagine a boot stamping on a human face — forever’: George Orwell
The battle is for your mind. Whenever you notice them doing it, open your mind even more. This letter was written by a bunch of worms. ABN
Your MIND Is The Battlefield In 5G War! Dr. Robert Malone Explains How Neural-Linguistic Programming Can Create ‘Zombie-Like’ Behavior In Humans
The Israel Attacks: Beyond the Obvious — Efrat Fenigson & Bret Weinstein
This is an excellent discussion, highly recommended. I will only add that I am delighted to learn Bret is a reader of ABN. ABN
Why Black Hole Environments Are a Lot More Complicated Than We Thought
Are we living in a simulation? Physicist claims he has new evidence we’re simply characters in an advanced virtual world
Melvin Vopson, an associate professor in physics at the University of Portsmouth, claims we may be characters in an advanced virtual world.
He claims that the physical behaviour of information in our universe resembles the process of a computer deleting or compressing code – a clue that perhaps the machines hope we don’t notice.
Professor Vopson has already warned of an impending ‘information catastrophe’, when we run out of energy to sustain huge amounts of digital information.
‘My studies point to a bizarre and interesting possibility that we don’t live in an objective reality and that the entire universe might be just a super advanced virtual reality simulation,’ Professor Vopson said.
Last year, the academic – from Romania – established a new law of physics, called the ‘second law of information dynamics’ to explain how information behaves.
His law establishes that the ‘entropy’, or disorder, in a system of information decreases rather than increases.
This new law came as somewhat of a surprise, because it’s the opposite of the second law of thermodynamics established in the 1850s, which explains why we cannot unscramble an egg or why a glass cannot unbreak itself.
As it turns out, the second law of infodynamics explains the behaviour of information in a way that the old law cannot.
Vopson’s paper: The second law of infodynamics and its implications for the simulated universe hypothesis featured
UPDATE: Information that is information about other information appears to be what we think of as consciousness, especially if that information is dynamic or able to focus and choose. Information may also be thought of as the stuff of karma, which itself can be thought of as a form of dynamic information, a coherent procession of information over time. This may even be the definition of time.
Consciousness as we know it is almost always dramatic; it almost always knows something or wants to know something or aims toward something or retreats from it. This is clearly true with regard to other people (or sentient beings) or within ourselves as our information parts interact (sort of what psychology is, or rumination). Regardless of whether human consciousness is high or low in the scheme of things, it tends to deeply crave meaning, purpose, reason, and is often satisfied with tautology over nothing, which proves or at least demonstrates this point :-)
Meaning and purpose are directional and organizational kinds of information. Since they are very common and arguably universal in everything we see, including the ‘lives’ of inanimate matter, it does seem that the whole of everything holds together around this point. In terms of information, it does not make much sense to say life itself is meaningless because what it is is a kind of meaning, a kind of procession of information. ABN
Efrat Fenigson interview — ‘There are some forces here that enabled this to happen, that allowed this to happen’
Israelis are experiencing an acute form of what Americans and Europeans have been experiencing for decades—their own government is somehow either complicit, infiltrated, or controlled by outside forces. And this has ‘allowed this to happen’. After 9/11 in the US, there were two main theoretical categories about what happened—our government MIHOP (Made It Happen On Purpose) or LIHOP (Let It Happen On Purpose). Israelis are also experiencing the Western sense that they do not even know who is in ultimate control of their nation. In USA, we have been experiencing for decades that whoever is in control of our government is doing to us what USA has been doing to the world for an even longer period of time. It seems that Israelis are now experiencing something similar, as are Europeans. There is a weird irony that many believe Israelis or Jews are the sinister power in control of USA and/or USA is the sinister power in control of Israel. Both could be true, of course. However you look at it, all signs do point to a secret cabal pulling the strings throughout the Western world, including Israel. And all signs point to that cabal having the ambition to conquer and control the world. ABN
The Biden Family Tree: How Investigations are Exposing the Bidens’ Influence-Peddling Dynasty
President Joe Biden once famously told a state official that “no one f—s with a Biden.” It was a statement that made more sense a few years ago than it does today.
These days, it seems like everyone is…well, messing with the Bidens. The president’s son, Hunter Biden, is facing federal charges on gun violations under a law that his father has heralded. He is also looking at possible additional charges on taxes.
Joe Biden’s brother James Biden was just subpoenaed alongside his nephew over millions of dollars sent by foreign figures as part of an influence-peddling operation.
Joe Biden is now formally under investigation for possible impeachment with at least four articles of impeachment under consideration.
Finally, a media that has long shielded the Bidens is now starting to acknowledge that Hunter and others were engaged in corrupt influence peddling.
All of this scrutiny is not simply threatening the Biden sense of invincibility. It is also revealing more about the Bidens behind the scenes in an unvarnished and unflattering light.
American Buddhist Net 