Both COVID-19 illness, caused by infection with the SARS-CoV-2 virus, and COVID-19 vaccination, ostensibly to prevent SARS-CoV-2 infection and serious COVID-19 morbidity, have been associated with the development of myopericarditis, i.e., inflammation of the heart muscle itself (myocarditis) or its suspending sack (pericarditis). This brief review demonstrates, first, the dubious association between SARS-CoV-2 infection and myopericarditis, and second, the robust association between COVID-19 vaccination, especially with mRNA vaccines, and myopericarditis, including, in particular, the study of fatal cases upon autopsy.
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