No small matter. Just below is the study. Below that is an article about the study.
The mRNA-based BNT162b2 vaccine from Pfizer/BioNTech was the first registered COVID-19 vaccine and has been shown to be up to 95% effective in preventing SARS-CoV-2 infections. Little is known about the broad effects of the new class of mRNA vaccines, especially whether they have combined effects on innate and adaptive immune responses. Here we confirmed that BNT162b2 vaccination of healthy individuals induced effective humoral and cellular immunity against several SARS-CoV-2 variants. Interestingly, however, the BNT162b2 vaccine also modulated the production of inflammatory cytokines by innate immune cells upon stimulation with both specific (SARS-CoV-2) and non-specific (viral, fungal and bacterial) stimuli. The response of innate immune cells to TLR4 and TLR7/8 ligands was lower after BNT162b2 vaccination, while fungi-induced cytokine responses were stronger. In conclusion, the mRNA BNT162b2 vaccine induces complex functional reprogramming of innate immune responses, which should be considered in the development and use of this new class of vaccines.The BNT162b2 mRNA vaccine against SARS-CoV-2 reprograms both adaptive and innate immune responses
I was very surprised to find this article referring to the study above on the front page of Google’s general news feed: Research suggests Pfizer-BioNTech COVID-19 vaccine reprograms innate immune responses.
Researchers in The Netherlands and Germany have warned that Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine induces complex reprogramming of innate immune responses that should be considered in the development and use of mRNA-based vaccines.Research suggests Pfizer-BioNTech COVID-19 vaccine reprograms innate immune responses
This kind of information is normally kept from the eyes of the general public. I wonder if it slipped through because the language is somewhat complex and studiously neutral. Of course, reprogramming our innate immune system is the biggest fear we have about these vaccines because once reprogrammed, the innate immune response will stay that way for decades, even a whole life. Changing something as complex as our natural immune system which is the fruit of millions of years of evolution is dangerous. Period. No doubt about that. Will these changes be passed on to offspring? Will they be contagious as the artificial spike proteins induced by the vaccines appear to be? What does an unplanned change in our immune response to fungi bode for the future? Clearly, these are not questions to be answered by vaccinating as much of the world as you can.